SingleSexual & Hormonal

HMG 75iu

Human menopausal gonadotropin delivering balanced FSH and LH activity for experimental endocrine and reproductive models.

Mechanism

HMG operates by concurrently binding FSH receptors on supporting reproductive cells to drive maturation processes and LH receptors to stimulate target endocrine steroidogenesis.

Dosing

Standard investigational regimens document an administration of 75 IU delivered three times per week.

Reconstitution

Adding 3.0 mL of bacteriostatic water to a 75 IU vial yields an operating concentration of 25 IU/mL.

Storage

Store unmixed lyophilized vials refrigerated between 2–8°C (35.6–46.4°F) protected from light, and use reconstituted liquid promptly while keeping cold.

Mix & measure HMG 75iu

Pre-filled with this protocol's recommended BAC water and documented starting dose — edit any field to run your own numbers.

Mix & measure HMG 75iu

Vial strength → BAC water → target dose

Vial strength

BAC water

Target dose

Concentration25.0mg/mL

Draw volume3.00mL

On the syringe300.0units

Total doses in vial: 1.0

100u80u60u40u20u0

U-100 syringe: 100 units = 1 mL

Reconstitution math only — not dosing advice. U-100 syringe: 100 units = 1 mL. Advanced calculator →

Dosing Chart

Phase / Day(s)	Dose & Frequency	Volume (U-100 units / mL)
Weeks 1–12	75 IU, 3×/week	3.0 mL (300 units)
Weeks 13–16 (optional)	75 IU, 3×/week	3.0 mL (300 units)

Reconstitution Steps

1
Draw 3.0 mL of bacteriostatic water using a sterile 3 mL syringe.
2
Introduce the fluid slowly down the interior glass wall of the HMG vial to prevent excessive foaming.
3
Gently rotate or swirl the vial between your palms until the powder fully dissolves without vigorous shaking.
4
Mark the vial with reconstitution time and refrigerate between 2–8°C (35.6–46.4°F) away from light.

Supplies Needed

Peptide Vial

Lyophilized HMG (75 IU per vial) for research exploration.

Insulin Syringes (U-100)

3 mL syringes or U-100 insulin syringes to measure and administer experimental volumes.

Bacteriostatic Water

Sterile diluent for reconstitution, requiring 3.0 mL per vial.

Alcohol Swabs

Used to sanitize vial stoppers and the designated application sites before each draw.

Why researchers study it

Spermatogenesis pathway activation

Dual FSH and LH receptor kinetics

Secondary hypogonadism models

Gonadal hormone maintenance alongside androgen suppression

These describe what is being studied, not proven benefits, approved uses, or promised results.

Overview

Human Menopausal Gonadotropin (HMG), also termed menotropins, is a biologically extracted gonadotropin composite that features roughly equivalent ratios of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) bioactivity. In laboratory and clinical research models, this dual-action profile makes it a crucial tool for investigating downstream gonadotropin receptor pathways, gametogenesis, and gonadal steroidogenesis. While clinically registered formulations of menotropins are used predominantly in female reproductive protocols, researchers frequently study HMG in male endocrinology paradigms. Specifically, it is utilized to assess Sertoli cell function, restoration of spermatogenesis, and intratesticular testosterone dynamics under circumstances where endogenous pituitary feedback mechanisms have been suppressed.

References

1.ASRM Practice Committee, Practice Committee Documents, 2020 — Clinical guidance on gonadotropins for ovulation induction
2.WADA, Prohibited List, 2024 — Regulations on gonadotropins and chorionic gonadotropin in male sports